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Channel: Aging and Lifespan – In the Pipeline
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The Samumed Story

Biopharma can be a weird place. Breakthroughs happen, although not as often as the press releases would have everyone believe, and we certainly don’t always see them coming. So when word comes of some...

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Subtle Changes Can Be Yours, for Fifty Dollars a Month

Several people have sent me a link to Elysium Health, and I can’t say that it’s improved my morning. This is a supplement company founded by (among others) Leonard Guarente of MIT, who is of course...

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A Shady Trial?

The “young blood” research field is moving right along, but there are reasons to wonder about some of the directions it’s moving in. I’m referring, of course, to the results that have shown profound...

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Isotopes, Get Your Revivifying Isotopes

Here’s your chance to get in on the ground floor – at least, the ground floor of a pitch you probably haven’t heard before. The chemists and biologists in the crowd will be familiar with how isotopic...

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Cellular Rejuvenation, For Real

There’s been a good amount of coverage of this paper, which is certainly worth a read. It concerns the “Yamanaka factors”, four proteins whose expression seems to be key for induced pluripotent stem...

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VCAM1 As a Player in the Aging Brain

Possible intervention targets for age-related degeneration are always welcome, particularly when they come bearing experimental evidence, and even more so when they relate to the central nervous...

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Metformin and Exercise

I’ve written about metformin quite a few times over the years on the blog, and for several reasons. It is (for starters) obviously a frontline drug for treatment of Type 2 diabetes, a condition that...

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Young Blood and Old Blood

So let’s do a non-coronavirus post for the weekend. Over the years, I’ve sporadically reported on the (rather contentious) field of aging and its biochemical implications. Many readers will recall the...

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Unity Biotechnology and Senescent Cell Therapy

Let’s have a look at the case of Unity Biotechnology, because this is a story that won’t get so many headlines. Unity has been investigating a really interesting but high-risk idea. It’s in the...

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Clearing Cellular Dead Wood

For many years now, the topic of “senescent cells” has been the subject of plenty of research work. Back in the 1960s the “Hayflick limit” was noticed in cell culture: there was an apparent limit to...

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